Indo-Asian scenario of microbes, infections, antibiotics and resistance - By Dr. A. J. Tamhankar (Research Associate: Sandeep Nerkar)

‘Colistin now has to be used routinely’- ‘poor sanitation necessitates antibiotics’; calls for government control over high-end antibiotics –  Times of India

“Task Force for Antibiotic Stewardship Kolkata” develop Antibiotic resistance  software to guide therapy, and have high hopes forit helping to improve empiric therapy –  Times of India

Singapore’s Agency for Science, Technology and Research (A*STAR) ’has signed an agreement with Astra-Zeneca to develop new drugs to treat Gram-negative infections’  - Channelnewsasia

Vietnam – “Antibiotic Resistance and Stewardship in Asia”; VINARES meeting held in Hanoi recently - ReAct 

India - high levels of MDR in bacteria in waste water treatment plants processing waste-water from bulk-drug production facilities; also, extraordinary levels of integrons – PLOS ONE

Hong Kong SAR – HongKong’s 35th case of NDM investigated, this time NDM-5 – HK Dep of Health 

Japan – MRSA problems in NICU, at least two cases, one death - Mainichi  

Swatting superbugs Indian Express.....A patient infected with an antibiotic-resistant strain of bacteria does not respond to antibiotic ...India, China, and Russia are most affected by MDR-TB cases.  

Superbug ate my arm: Woman's terrifying encounter with flesh ...The Australian.....The patient's only hope against this wildly aggressive bacterial infection ... This is already the case in India where antibiotics have been sold over the counter for ... The rush of antibiotics that kept treatment ahead of resistance has slowed to a ... 

Doctors alarmed as antibiotics lose efficacy Times of India......The bacterial disease burden in India is among the highest in the world. Also, a significantly large population is at risk of secondary infections through ... Antibiotic resistance is a resistance of bacteria,such as E. coli which causes ... 

Ramanan Laxminarayan: The Global Reach of ResistanceFRONTLINE....Because of these drugs, we don't die of infection diseases. ... And over time, the entire population of bacteria in the environment, in our bodies, are... They're more likely to die, and in poor countries like India and Sub-Saharan Africa, .... Second,it conferred resistance to nearly all the important antibiotics wehad against ...

Indo-Asian scenario of microbes, infections, antibiotics and resistance - By Dr. A. J. Tamhankar (Research Associate: Sandeep Nerkar)

Bacteria growing increasingly resistant to drugs......Daily News & Analysis.....When a patient develops resistance towards a drug, he might need stronger antibiotics the next time he gets a bacterial infection, and the side-effects and ... 


Aurora Sinai patient has 'nightmare bacteria' infection..... Milwaukee Journal Sentinel....A patient with an infection caused by a deadly superbug that federal officials ... they infect because the bacteria are highly resistant to antibiotics, ... 

Aurora Sinai patient has 'nightmare bacteria' infection MENAFN.COM.....Those countries where CRE are an issue includeIndia, Greece, Italy, Pakistan and ... they infect because the bacteria are highly resistant to antibiotics, ... 

Medical curriculum must be modernised, says Chennai doctor.....The Hindu.....The Indian medical curriculum must be modernised to provide training in rational antibiotic use and infection control for all medical students, Abdul Ghafur ... 

Socialize Big Pharma! Salon... in India a few years ago. Ricci suffered infections from drug-resistant bacteria that even highly toxic last-resort antibiotics could not treat. 

Extensive use of antibiotics may lead Kolkata to a disaster ...Times of India  

Cluster of two CA-MRSA cases under CHP investigation.... Hong-Kong SAR 

Improved understanding of factors driving methicillin-resistant Staphylococcus aureus epidemic waves

http://www.dovepress.com/articles.php?article_id=13563


Improved understanding of factors driving methicillin-resistant Staphylococcus aureus epidemic waves

Abstract: Methicillin-resistant Staphylococcus aureus (MRSA) remains one of the most important causes of nosocomial infections worldwide. Since the global spread of MRSA in the 1960s, MRSA strains have evolved with increased pathogenic potential. Notably, some strains are now capable of causing persistent infections not only in hospitalized patients but also in healthy individuals in the community. Furthermore, MRSA is increasingly associated with infections among livestock-associated workers, primarily because of transmission from animals to humans. Moreover, many MRSA strains have gained resistance to most available antibiotics. In this review, we will present current knowledge on MRSA epidemiology and discuss new endeavors being undertaken to understand better the molecular and epidemiological underpinnings of MRSA outbreaks.

Keywords: Staphylococcus aureus, MRSA, nosocomial infection, community-associated infection

Govt mulling ban on sale of TB drugs in open market

 

[http://www.thehindu.com/sci-tech/health/policy-and-issues/govt-mulling-ban-on-sale-of-tb-drugs-in-open-market/article4880960.ece]

BL A protest in Mumbai against the developed countries move to block access to HIV and TB drugs.

TOPICS

Sale of tuberculosis drugs could be prohibited in open market as part of efforts to ensure calibrated and monitored administration of these medicines which would then only be given on daily basis free of cost by government registered outlets to patients.

The Health Ministry is proposing changes in view of irregularity in administration of these drugs to patients and lack of proper monitoring which is hindering efforts to check the disease, sources told PTI.

According to a WHO estimate, India is home to the largest number of TB patients - 2.2 million of the world’s 8.7 million.

Patients are administered TB medicines either through government-run hospitals and clinics free of cost or by private practitioners.

According to the Health Ministry, about 65 per cent of the TB patients avail these drugs under the government’s DOT (Daily Observed Therapy) System while the rest opt for treatment by private practitioners and buy drugs from the chemists based on their prescription.

The latter results in irregularity of treatment which leads to relapse of the ailment as there is lack of proper monitoring, the sources said citing experts.

To address this, the government is planning to prohibit sale of drugs in open market.

Under the new initiative, patients going to private practitioners for treatment will get medicines free of cost from chemists but only after the doctor informs them through a dedicated call centre to be set up by the government.

The changes are being brought to ensure that all TB patients are administered the drugs on daily basis instead of intermittently as at present.

Recently, Health Minister Gulam Nabi Azad had expressed concern on the issue saying that the irregular regime is leading to growing resistance to anti-TB drugs.

The Health Ministry officials recently had held a meeting with WHO and other experts who had emphasised on changing intermittent dosage system to daily regime.

During the meeting, it was informed that many other countries including Brazil, China, which were following the intermittent dosage system, have now turned to daily regime.

 

Keywords: Health Ministry, WHO, TB drugs, Government hospitals, Treatment schedule, Sale of drugs, DOTS

Indo-Asian scenario of microbes, infections, antibiotics and resistance - By Dr. A. J. Tamhankar (Research Associate: Sandeep Nerkar)

The Times of India reports that India faces a severe shortage of pediatric and drug-resistant tuberculosis drugs. [Times of India]

The booming illegal trade of usedmedical equipments and hospital waste is posing a serious threat to public health in Pakistan. [Pakistan Today]

Screening the national population in India for HIV every five years is cost-effective and could save millions of lives, according  to a study  published in the journal PLoS One. [Futurity]

Indo-Asian scenario of microbes, infections, antibiotics and resistance - By Dr. A. J. Tamhankar (Research Associate: Sandeep Nerkar)

India– ”we’re heading for a post-antibiotic stage?” says Dr Camilla Rodrigues at a conference, and emphasizes the role of sanitation facilities; Indian Express  

Providing Impetus, Tools, and Guidance to Strengthen National Capacity for Antimicrobial Stewardship in Viet Nam   

Antimicrobial Resistance Challenges Faced In Vietnam

The dearth of new antibiotics, the Times of India cites a CDDEP study on the overuse of antibiotics in India 

Indo-Asian scenario of microbes, infections, antibiotics and resistance - By Dr. A. J. Tamhankar (Research Associate: Sandeep Nerkar)

India – ”fight those super bugs” – in an article in the Hindu, it is pointed out that the Indian government formulated a policy for antibiotic resistance containment in 2011 – ”however, effective execution is a huge challenge”  

India – a pessimistic tone on the present standing of antibiotics, by a microbiologist in Mumbai; focus needs to be on improving public sanitation conditions, she says – The Hindu 

Malaysia – workshop on international health and antibiotic resistance, reported from by ReAct 

Hong Kong SAR – investigating its 27th detected case of NDM-1 – Dept of Health

Japan – VRE outbreak in a hospital in Okayama, in two waves, totally 21 cases – Sankei.msn  

Among Antibiotics,Resistance Knows No Bounds: Pacific Standard...But with the emergence of antibiotic resistance genes, some of which make infectious bacteria invulnerable to all known antibiotic medications, ... 

Rise indrug-resistant bugs due to overuse of antibiotics: Times of India....NEW DELHI: Overuse of antibiotics has led to a situation in which even simple infections acquired outside the hospital are turning drug-resistant.

India 'Has Lost' Superbug War: Wall Street Journal....Bacteria carrying the NDM-1enzyme are highly resistant to the most powerful group of antibiotics,known as carbapenems, making infections caused by them ...

Bacteria are becoming bolder: The Hindu....He was treated with high doses of a toxic antibiotic. ... Moreover, we are seeing infections with resistant bacteria being acquired from the community, ... 

Drug-resistant bacteria on the rampage, says expert: The Hindu.....Though bacterial resistance to common antibiotics was a world-wide concern,the magnitude of the problem was much more in India across the three main ....

Antibiotic Resistance in Egg Farm Study Raises Concerns: The Poultry Site.com....INDIA - About three per cent of egg and environmental samples from farms in ... but the relatively high antibiotic resistance among the bacteria was raised ... 

The Nearly Unstoppable Superbugs: Yahoo! News....Many antibiotics are designed to kill bacteria by destroying a single cell ... of a man hospitalized in India with a not-so-uncommon urinary tract infection ... 

Indo-Asian scenario of microbes, infections, antibiotics and resistance - By Dr. A. J. Tamhankar (Research Associate: Sandeep Nerkar)

India – banning of OTC sales of antimicrobials discussed in morning TV, by ia CDDEP Director Laxminarayan– rural availability must be considered  - CDDEP, and IBN

Nepal – Antibiotic Resistance, an increasing public health threat; as conveyed by  The Himalayan Times

China – Swedish MoH visits the Chinese counterpart, to discuss continued cooperation;  i a antibiotic resistance and primarycare is on the agenda  – Regeringen 

Hong Kong SAR – 26th case of NDM-1, a five-year old boy with blood stream infection after hospital stay in Pakistan  – News.Gov.HK

India – internationalappreciation pours in for the Chennai declaration, and now it is taken up for discussion by Ministry of Health  –The Hindu

Indo-Asian scenario of microbes, infections, antibiotics and resistance - By Dr. A. J. Tamhankar (Research Associate: Sandeep Nerkar)

China, India travel boosts risk of antibiotic resistant cystitis..The Conversation.....“My guess would be that well over 50% of people who go to India do not come back with antibiotic resistant bacteria that cause an infection. We are not warning people not to go to Southeast Asia or India,” he said. “It's more that if we go overseas ...


Now, an antibiotic protocol on cards.....Times of India.....It was time for every region and city to have an antibiotic protocol for the nature and type of bacteria vary from one place to another. "Our policy can't be guided by international norms for the nature of infection and the type of bacteria is vastly  

Antibiotic resistance on the rise in India....IBN Live....There is also the larger burden of drug resistant bacterial infections, especially hospital infections. Center for Disease Dynamics, Economics & Policy (CDDEP) Director Dr Ramanan Laxminarayan said, "The fact is that we are soon approaching a stage ... 

Drug alert system by CDSCO picks up momentum

Joseph Alexander, New Delhi

The drug alert system, launched by the Central Drugs Standard Control Organisation (CDSCO) to inform the public about the drugs, devices and cosmetics found substandard or spurious during the tests, has picked up momentum with different drug testing laboratories reporting 12 cases during January. After the system was launched in November with three cases that came from the Central Drug Testing Lab in Chennai alone, the number of such cases went to seven with more labs sending in reports to the DCGI office in December. The alert system also has prompted the companies to recall the batches of drugs found substandard. CDL, Kolkota has reported four cases while regional central drug testing lab of Guwahati and CDTL, Chennai reported three cases each in January. Regional lab at Chandigarh and CDTL in Mumbai also sent reports about one each cases. Brexic DT (piroxicam dispersible tablets 20 mg) having batch no. WBI-1207 and manufactured by Wockhardt Ltd was among the cases reported. Cloxacid- D 500 capsules (bath no WGS 1204) by G S Pharmaceuticals was sent by Arunachal Pradesh Drugs Control Department to RDTL Guwahati and was  found substandard in the assay test in another instance. Adrenaline injection IP (b.no – AD1N1L) by Arco Life Sciences of Nagpur,  telmisartan and hydrochlorothiazide tablets USP (Arbitel-H) having batch number of ARHD0029 and manufactured by Micro Labs of Baddhi,  diclofenac sodium tablets IP 50 mg (Batch No. DF110) by Eurokem Laboratories (P) Ltd of Alathur in Tamil Nadu, and Spasdor tablets (dicyclomine HCL and mafenamic acid tablets) having batch No. JKT-12107 and manufactured by Japsi Chem Pharmaceuticals of Solan were also among those reported as substandard.  Another drug, Pyricure-650 (paracetamol tablets) with batch No. JLT-1221, manufactured by Japsi was also found substandard in the test done by Chennai lab. Spinz talcum powder (batch no L3) by Cavincare Pvt Ltd failed the test for microbial limit while Oroceph-500 capsule (batch no OC5-7033) by Lark Laboratories was found to be having no uniformity with that of net content. Lupisera-D tablets (b.no. 005 E1ABY) by Akums Drugs and Pharmaceuticals Ltd, Carvas 3.125 (carvedilol tablets IP) with batch no of E20053 manufactured by Medley Pharmaceuticals and Ondasentron tablets (B.No 1103) by Deepin Pharmaceuticals were also included in the alert list.

Indo-Asian scenario of microbes, infections, antibiotics and resistance - By Dr. A. J. Tamhankar (Research Associate: Sandeep Nerkar)

Antibiotic against cough loses potency, thanks to random use-Times of India...NEW DELHI: One of India's most commonly used antibiotic against cough has become ... "Most bacteria will ultimately become resistant to antibiotics if taken ... 
Is the antibiotic against cough actually bad for us? India.Com Health... antibiotic amoxicillin, regularly prescribed for bacterial infections of the chest, ... In India, it's usually used to treat cough and lower respiratory ...
Bacteria causing UTI infections becoming immune to drugs :Daily Pioneer....E. coli bacteria, a major cause for urinary tract infections (UTI), is increasingly becoming resistant to the most prescribed antimicrobial, ...
Hong Kong SAR – ’MRSA levelling off’; seems like more MRSA in society than in the hospitals – South China Morning Post
India –  a study on amoxicillin against non-pneumonic RTI, published in Lancet Infectious Diseases, is also reviewed in Times of India

Pakistan – hospital hygiene and cleaning seems to be at a verylow level in at least some hospitals – The Express Tribune

Bad bugs rate 40% higher in Indian ICUs than general war