Indo - Asian Antibiotic News 2009 - Dr.A.J.Tamhankar

In Media
WHO Sponsors Event At Copenhagen Conference To Highlight Climate Change Effect On Public

Indo - Asian Antibiotic News 2009 - Dr.A.J.Tamhankar

In Media
Researchers are relying on nanoparticles to heal skin abscesses caused by strains of bacteria that resist antibiotics.
Low immunization levels in Uttar Pradesh causing concern: Unicef. It is resulting in the resurgence of diseases like diphtheria and whooping cough in children.

Indo - Asian Antibiotic News 2009 - Dr.A.J.Tamhankar

In the Indian Media
Exposure to infectious microbes early in life may protect individuals from diseases in adult stage.
Bacteria Offer Insights into Human Decision Making
Traditional Indian remedies digitised

Indo - Asian Antibiotic News 2009 - Dr.A.J.Tamhankar

Obama Issues Joint Statement With Indian Prime Minister Singh, Includes Health, Agriculture Collaboration
From the journals:
Magnitude of drug resistant Shigellosis: a report from Bangalore.
Molecular characterization of a full-length genome of a HIV-2 isolate from India.
Low frequency of moaA3 gene among the clinical isolates of Mycobacterium tuberculosis from Tamil Nadu and Pondicherry--south eastern coastal states of India.
Enterococci in river Ganga surface waters: propensity of species distribution, dissemination of antimicrobial-resistance and virulence-markers among species along landscape.
Ciprofloxacin breakpoints in enteric fever: time to revise our susceptibility criteria.
Drug resistant mutations detected by genotypic drug resistance testing in patients failing therapy in clade C HIV-1 infected individuals from India.
Clustering analysis of Salmonella enterica serovar Typhi isolates in Korea by PFGE, ribotying, and phage typing.

Alzheimer`s disease and New antibiotics-By A.J. Tamhankar

Scientists from Washington University School of Medicine in St. Louis have revealed that amyloids, known to be responsible for causing Alzheimers disease, have been found to play a critical role in urinary tract infections. Some of the infectious bacteria use amyloids to attach to host cells and to build biofilms, which are bacterial communities bound together in a film that helps resist antibiotics and immune attacks. During the study, the research team altered potential UTI-fighting compounds originally selected for their ability to block bacteria's ability to make amyloids and form biofilms. But when they brought the compounds back to UTI research after the neurology studies, they found the changes had also unexpectedly made them more effective UTI treatments. (From Andhra News)

Indo - Asian Antibiotic News 2009 - Dr.A.J.Tamhankar

Urine test may help diagnose pneumonia early
GE keen to bring quality healthcare to Indian villages

Indo - Asian Antibiotic News 2009 - Dr.A.J.Tamhankar

-On 8th December, 2009, International aid agency Global Fund announced a $128.5 million grant for India to fight AIDS, tuberculosis and malaria. Of the grants, $69.4 million will be provided for expanding care and treatment services for tuberculosis (TB), particularly for multi-drug resistant tuberculosis. India bears 21 percent of the global TB burden and has the highest estimated incidence of multi-drug resistant cases of any country. $38.1 million will go to malaria prevention and treatment efforts in the seven states in the northeast region - Arunachal Pradesh, Assam, Manipur, Meghalaya, Mizoram, Nagaland and Tripura. This includes efforts to achieve near universal coverage of long-lasting insecticide treated nets by 2015 in these areas. $18.6 million will go to multi-country HIV grant in South Asia for an initiative targeting gays and the transgender community.
-The patent expiries of three blockbuster antibiotics —levofloxacin, moxifloxacin and piperacillin /tazobactam — in the near future may contribute to their cheaper availability in countries like India.

Indo - Asian Antibiotic News 2009 - Dr.A.J.Tamhankar

From the Media
Ayurvedic tradition has it that drinking water on an empty stomach that has been stored overnight in a copper urn keeps illness at bay. A scientific experimentation News in Times of India (December 03, 2009) confirms that Copper keeps superbugs at Bay.

Indo - Asian Antibiotic News 2009 - Dr.A.J.Tamhankar

From the Media
Vitamin D is nature`s antibiotic- Times of India-Nov 25, 09

Indo - Asian Antibiotic News 2009 - Dr.A.J.Tamhankar

From the Indian Media
Bacteria living on the surface of the skin help in maintaining its healthy texture, says a new study.-The Hindu
Wipro Technologies has developed a medical gateway solution for remote healthcare management on real-time basis through mobile, broadband and dial-up networks

Indo - Asian Antibiotic News 2009 - Dr.A.J.Tamhankar

From the Indian Media
Task force set up by Indian Council of Medical Research (ICMR) to formulate guidelines for regulatng pro-biotic food
The Indian health ministry will spend Rs.9.2 billion this financial year for promoting Ayurveda, Yoga & Naturopathy
Viruses that target bacteria potentially open up new ways to treat bacterial infections

Indo - Asian Antibiotic News 2009 - Dr.A.J.Tamhankar

From the Media
Emergence of Hyper-resistant bacteria : A Global threat - Says ECDC on Antibiotic Awareness Day (Times of India)

Indo - Asian Antibiotic News 2009 - Dr.A.J.Tamhankar

Media News :
Pakistan – ABR; ”irrational use of antibiotics has eliminated the good bacteria and encouraged bad, resistant bacteria” it was said during a large Medical Conference
Overuse of antibiotics can make you drug resistant: Experts - Times of India
Cough into your mobile phone for instant diagnosis - A news item in Times of India
Computerised alerts can curb prescription of costly drugs
Faulty immune memory can trigger cold sores, cancer
Laugh your way to good health
President of India launches Gateway Portal to connect with rural poor

From Journals :

In vitro activity of daptomycin against Staphylococcus aureus and vancomycin-resistant Enterococcus faecium isolates associated with skin and soft tissue infections: first results from India.
Vancomycin resistant Enterococci in a tertiary care hospital in Mumbai.
Anti-microbial resistance stratified by risk factor among Escherichia coli strains isolated from the urinary tract at a rural clinic in Central India.
Emergence of high levels of extended-spectrum-beta-lactamase-producing gram-negative bacilli in the Asia-Pacific region: data from the Study for Monitoring Antimicrobial Resistance Trends (SMART) program, 2007.
Evaluation of two human immunodeficiency virus-1 genotyping systems: ViroSeq 2.0 and an in-house method.
Ventilator-associated pneumonia caused by carbapenem-resistant Enterobacteriaceae carrying multiple metallo-beta-lactamase genes.
High levels of multidrug resistant tuberculosis in new and treatment-failure patients from the Revised National Tuberculosis Control Programme in an urban metropolis (Mumbai) in Western India.

Indian Antibiotic Resistance Scenario - 2009 (by A.J. Tamhankar)

Media News
Scientists can eavesdrop on bacteria and learn how they chat with one another
The Confederation of Indian Industry and the U.S.-India Business Council have announced a “Coalition for Healthy India”.
Eight cups of tea a day can boost your heart and brain
Fruit Juices are 'immunity builders'
Cellphone to diagnose diseases

Indian Antibiotic Resistance Scenario - 2009 (by A.J. Tamhankar)

Media News:

Lower fat hormone levels turn blood infection deadly

Health centres have to manage waste effectively: Experts

Soldiers more vulnerable to tropical diseases

Indian Antibiotic Resistance Scenario - 2009 (by A.J. Tamhankar)

Media News:

Indian researchers get Bill and Melinda Gates grants - (One project - hand-held electronic nose which can ’smell’ tuberculosis.)

Doctors call for more investment in public health

Eat right, nurture good bacteria in your gut

Child groups to observe Nov 2 as World Pneumonia Day

Doctors least likely to wash hands: Study

Scientific Journals ........Human - 2009

Assessing clonality of Vibrio cholerae strains isolated during four consecutive years (2004 - 2007) in Iran.

Recent experience with fungaemia: change in species distribution and azole resistance.

Multidrug resistant enteroaggregative Escherichia coli diarrhoea in rural southern Indian population.

Re-emerging chloramphenicol sensitivity and emerging low level ciprofloxacin resistance among Salmonella enterica serotype typhi isolates in North India.

Detection of virulence genes in Vibrio cholerae isolated from aquatic environment in Kerala, Southern India.

Increasing invasive disease due to penicillin resistant S. pneumoniae in India.

Penicillin-resistant viridans group streptococci from blood cultures of infective endocarditis patients in South India.

Detection of Pseudomonas aeruginosa isolates producing VEB-type extended-spectrum beta-lactamases in the United Kingdom.

Determination of antimicrobial resistance and virulence gene signatures in surface water isolates of Escherichia coli.

Antibiotic prescribing practices in primary and secondary health care facilities in Uttar Pradesh, India.

Prevalence of extended spectrum beta-lactamases producing clinical isolates from patients of urinary tract infection in a tertiary care hospital in Delhi.

Paediatric tuberculosis and DOTS strategy under RNTCP.

Emerging Gram-negative antibiotic resistance: daunting challenges, declining sensitivities, and dire consequences.

The cost-effectiveness of typhoid Vi vaccination programs: calculations for four urban sites in four Asian countries.

Class 1 integrons and SXT elements conferring multidrug resistance in Vibrio cholerae O1 strains associated with a recent large cholera outbreak in Orissa, Eastern India.

Multidrug-resistant to extensively drug resistant tuberculosis: what is next?

Emerging antibiotic resistance in bacteria with special reference to India.

Emerging and re-emerging bacterial diseases in India.

HIV and tuberculosis in India.

Indo - Asian Antibiotic News 2009 - Dr.A.J.Tamhankar

In Media----Eating frequently may keep fungi at bay- (NewKerala.com); Washing hands can save 400 children everyday: Unicef- (Times of India); Online course in tuberculosis treatment launched-(Samachar.in); Diarrhoea kills 1.5 mn children annually: UN- (South Asia News)

Indian Antibiotic Resistance Scenario - 2009 (by A.J. Tamhankar)

Scientific Journals------Human-2009

Diversity of arsenate reductase genes (arsC Genes) from arsenic-resistant environmental isolates of E. coli.
Increasing rates and clinical consequences of nalidixic acid-resistant isolates causing enteric fever in returned travellers: an 18-year experience.

Evaluation of two human immunodeficiency virus-1 genotyping systems: ViroSeq 2.0 and an in-house method.

Low frequency of moaA3 gene among the clinical isolates of Mycobacterium tuberculosis from Tamil Nadu and Pondicherry--south eastern coastal states of India.

Enterococci in river Ganga surface waters: propensity of species distribution, dissemination of antimicrobial-resistance and virulence-markers among species along landscape.

Clustering analysis of Salmonella enterica serovar Typhi isolates in Korea by PFGE, ribotying, and phage typing.

Ciprofloxacin breakpoints in enteric fever: time to revise our susceptibility criteria.

Drug resistant mutations detected by genotypic drug resistance testing in patients failing therapy in clade C HIV-1 infected individuals from India.

Molecular characteristics of travel-related extended-spectrum-beta-lactamase-producing Escherichia coli isolates from the Calgary Health Region.

Risk factors for antibiotic-resistant E. coli in children in a rural area.

Analysis of antimicrobial resistance and plasmid profiles in Salmonella serovars associated with tropical seafood of India.

In vitro drug resistance and response to therapy in pulmonary tuberculosis patients under a DOTS programme in south India.

Role of embCAB gene mutations in ethambutol resistance in Mycobacterium tuberculosis isolates from India.

Outbreak of meningococcal disease in and around New Delhi, India, 2005-2006: a report from a tertiary care hospital.

Drug resistance in Mycobacterium tuberculosis isolates from tuberculosis patients in Kerala, India.

Phenotypic and genotypic assays for detecting the prevalence of metallo-beta-lactamases in clinical isolates of Acinetobacter baumannii from a South Indian tertiary care hospital.

Carbapenem resistance among Pseudomonas aeruginosa strains from India: evidence for nationwide endemicity of multiple metallo-beta-lactamase clones (VIM-2, -5, -6, and -11 and the newly characterized VIM-18).

Surveillance of invasive pneumococcal disease in Colombo, Sri Lanka.

In vitro activity of gentamicin and amikacin against Salmonella enterica serovar Typhi: a search for a treatment regimen for typhoid fever.

High-level aminoglycoside resistance and beta-lactamase production in enterococci at a tertiary care hospital in India.

Surface water of a perennial river exhibits multi-antimicrobial resistant shiga toxin and enterotoxin producing Escherichia coli.

Outbreaks caused by new variants of Vibrio cholerae O1 El Tor, India.

XDR Tuberculosis: a report from the New Delhi Tuberculosis Centre, India.

Molecular characterization of Vibrio cholerae isolates from cholera outbreaks in North India.

Activity of antibiotics against Fusarium and Aspergillus.

Self-purificatory Ganga water facilitates death of pathogenic Escherichia coli O157:H7.

An increase in enteric fever cases due to Salmonella Paratyphi A in & around Chandigarh.

Gradual filling up of TB drug pipeline: how can we play our role better?

Increasing incidence of fluoroquinolone-resistant Mycobacterium tuberculosis in Mumbai, India.

Acquired drug resistance pattern in tuberculosis cases at the State Tuberculosis Centre, Delhi, India.

Molecular epidemiological characteristics of Shigella spp. isolated from river Narmada during 2005-2006.

HIV-1 with predicted CXCR4 genotype identified in clade C from India.

A prospective, descriptive study to identify the microbiological profile of chronic wounds in outpatients.

In-depth molecular characterization of Mycobacterium tuberculosis from New Delhi--predominance of drug resistant isolates of the 'modern' (TbD1) type.

Indo - Asian Antibiotic News 2009 - Dr.A.J.Tamhankar

A report from medindia -Call For Mandatory Reporting Of Golden Staph Bloodstream Infections, Australia

Clinical Trial Launched In India To Improve Treatment For People Bitten By Rabid Animals

Simple test can sniff out tuberculosis bacteria - A news in Prokerala

Nobel winner Venki's work as important as penicillin discovery: UK minister - news from Times of India

Indian Antibiotic Resistance Scenario - 2009 (by A.J. Tamhankar)

Media News - - How do bacteria subvert healthy cells?
Scientific Journals------Human-2009
Magnitude of drug resistant Shigellosis: a report from Bangalore.
Antimicrobial resistance and in vitro gene transfer in bacteria isolated from the ulcers of EUS-affected fish in India.
The role of a novel efflux pump AbeS, member of the SMR family of transporters in resistance to antimicrobial agents in Acinetobacter baumannii.
Characterization of a New Metallo-{beta}-lactamase gene, blaNDM-1, and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India.
Codon usage and gene expression pattern of Stenotrophomonas maltophilia R551-3 for pathogenic mode of living.
Development of a phosphomannose isomerase-based Agrobacterium-mediated transformation system for chickpea (Cicer arietinum L.).
Isolation and sequence analysis of a small cryptic plasmid pRK10 from a corrosion inhibitor degrading strain Serratia marcescens ACE2.
Evolution of antimicrobial resistance in enteroaggregative Escherichia coli and enterotoxigenic Escherichia coli causing traveller's diarrhoea.
Role of persisters and small-colony variants in antibiotic resistance of planktonic and biofilm-associated Staphylococcus aureus: an in vitro study.
Antifungal activity of Glycyrrhiza glabra extracts and its active constituent glabridin.
On the potential of Tephrosia purpurea as anti-Helicobacter pylori agent.

Indian Antibiotic Resistance Scenario - 2009 (by A.J. Tamhankar)

Go easy on Paracetamol, it could hurt liver
Nano lotion curbs burns infection thousand times
New initiatives of the health ministry
Fighting diarrhoea to eradicate polio

Indo - Asian Antibiotic Resistance Scenario 2009

Alarmingly high level of AB prescription, as well as AB resistance in Delhi.
Fighting diarrhoea to eradicate polio
Showers can drench you with pathogens
Popular antacid triples pneumonia risk

Indo-Asian Antibiotic Resistance Scenario - 2009

A Highly successful Antibiotic Resistance Awareness Campaign at Tiruchirapalli, Tamil Nadu, India - A report by Dr. A.J. Tamhankar

Indo-Asian Antibiotic Resistance Scenario - 2009 (by A.J. Tamhankar) Scientific Journals------Human use-2009.

-Extended spectrum beta-lactamases in Escherichia coli & Klebsiella pneumoniae & associated risk factors.
-Epidemiology & antibiograms of Vibrio cholerae isolates from a tertiary care hospital in Chandigarh, north India.
-Low frequency of moaA3 gene among the clinical isolates of Mycobacterium tuberculosis from Tamil Nadu and Pondicherry--south eastern coastal states of India.

Antibiotic Resistance Management Initiative spreading across the country

GARP-India Meeting and IIMAR campaign on Rational use of Antibiotics start on 24th August 2009. For details see http://save-antibiotics.blogspot.com/

Indo-Asian Antibiotic Resistance Scenario - 2009 (by A.J. Tamhankar) Media News-----Scientists make new drug to kill tough bugs.--------11 die of diarrhoea in Orissa.-------Antibiotic resistance is a silent killer but more powerful than swine flu.

Indo-Asian Antibiotic Resistance Scenario - 2009 (by A.J. Tamhankar) Media News-------Mango kernels can protect against deadly food bacteria.

Indo-Asian Antibiotic Resistance Scenario - 2009 (by A.J. Tamhankar) Media News-----Text Messages To Fight Polio; TB At Pakistani Relief Camps; ARV Supply In Uganda.-------Asian Pneumonia Prevention Organization Calls For Required Pneumonia Vaccine In India.
Scientific Journals------Human-2009

-On the potential of Tephrosia purpurea as anti-Helicobacter pylori agent.
-Molecular epidemiological analysis of methicillin-resistant Staphylococcus aureus isolates from Chinese pediatric patients.
-Increased prevalence and clonal dissemination of multidrug-resistant Pseudomonas aeruginosa with the blaIMP-1 gene cassette in Hiroshima.

Indo-Asian Antibiotic Resistance Scenario - 2009 (by A.J. Tamhankar) Media News---------Pathogens come programmed with their own death.---------Centre to spend Rs 510 cr on upgrading National Institute of Communicable Diseases.

Indo-Asian Antibiotic Resistance Scenario - 2009 (by A.J. Tamhankar) Media News---------Can hospitals cope with a large-scale bio-terror attack?--------Researchers capture live images of how bacteria infect host. ------Researchers develop painless test for Chlamydia.

Indo-Asian Antibiotic Resistance Scenario - 2009 (by A.J. Tamhankar) Media News-----Health Ministry to launch project to stop indiscriminate sale of TB drugs.------------DSM Anti-Infectives sets up facility at Punjab.----------Amend laws, give dignity to the leprosy hit.
Scientific Journals------Human-2009

-A Multinational Survey of Risk Factors for Infection with Extended-Spectrum beta-Lactamase-Producing Enterobacteriaceae in Nonhospitalized Patients.

Indo-Asian Antibiotic Resistance Scenario - 2009 (by A.J. Tamhankar)
Media News-------Fatal case of community-associated MRSA. -------- Film Director and Choreographer Farah Khan promotes pneumococcal conjugate vaccine for kids.

Indo-Asian Antibiotic Resistance Scenario - 2009 (by A.J. Tamhankar)
Media News-------Pakistani Refugees Continue To Be At High Risk For Disease.-------Major pharma cos commence human trials of seven candidate TB drugs.

Indo-Asian Antibiotic Resistance Scenario - 2009 (by A.J. Tamhankar)Scientific Journals------Human-2009.

-Genetic determinants of virulence, antibiogram and altered biotype among the Vibrio cholerae O1 isolates from different cholera outbreaks in India.

Indo-Asian Antibiotic Resistance Scenario - 2009 (by A.J. Tamhankar) Media News-----Weird sex, secret of bacterial resistance to antibiotics.--------Bacteria-killer proteins may yield new medicines.
Scientific Journals------Human-2009.
-Role of persisters and small-colony variants in antibiotic resistance of planktonic and biofilm-associated Staphylococcus aureus: an in vitro study.

Indo-Asian Antibiotic Resistance Scenario - 2009 (by A.J. Tamhankar) Media News-----Shared keyboards are hot spots for infection.---------New lab-on-a-chip sizes up bacteria colonies.-------Peptic ulcer bug manipulates immune system.
Scientific Journals------Human-2009.
-Molecular characterisation of outbreak-related strains of vancomycin-resistant Enterococcus faecium from an intensive care unit in Beijing, China.

Indo-Asian Antibiotic Resistance Scenario - 2009 (by A.J. Tamhankar)
Scientific Journals------Human-2009.

-High rate of reduced susceptibility to ciprofloxacin and ceftriaxone among nontyphoid Salmonella clinical isolates in Asia.
-Molecular characteristics of travel-related extended-spectrum-beta-lactamase-producing Escherichia coli isolates from the Calgary Health Region.

Indo-Asian Antibiotic Resistance Scenario - 2009 (by A.J. Tamhankar)

Scientific Journals------Human-2009.

-Study on acquisition of bacterial antibiotic resistance determinants in poultry litter.

Indo-Asian Antibiotic Resistance Scenario - 2009 (by A.J. Tamhankar) Media News-----Statins 'don't cut' pneumonia risk in elderly.
Scientific Journals------Human-2009.
-Waterways Polluted With Antibiotics, Antimicrobials And Antifungals.

Indo-Asian Antibiotic Resistance Scenario - 2009 (by A.J. Tamhankar) Media News-----Statins 'don't cut' pneumonia risk in elderly.

Indo-Asian Antibiotic Resistance Scenario - 2009 (by A.J. Tamhankar) Media News-------Unicef musters more financial aid to fight pneumonia.
Scientific Journals------Human-2009.

-Treatment of bacterial meningitis: an overview of Cochrane systematic reviews.

Indo-Asian Antibiotic Resistance Scenario - 2009 (by A.J. Tamhankar)
Media News-------Antibiotic Resistance Advance In Asia - Growing Resistance Of Paratyphoid Fever Bacterium.

Scientific Journals------Human-2009.

-Antiplasmid activity of 1'-acetoxychavicol acetate from Alpinia galanga against multi-drug resistant bacteria.

Indo-Asian Antibiotic Resistance Scenario - 2009 (by A.J. Tamhankar)

Media News--------Antibiotics in environment, Hyderabad, India.---------Oldest Evidence Of Leprosy Found In India.

Indo-Asian Antibiotic Resistance Scenario - 2009 (by A.J. Tamhankar)
Media News-----ICMR to develop projects to assess reasons for detection of new cases of leprosy. ---------Study throws light on unexpected bacterial diversity in human skin.

Indo-Asian Antibiotic Resistance Scenario - 2009 (by A.J. Tamhankar)

Media News-------How superbugs control their lethal weapons.------Turnover of five Pharma PSUs increased by 112% in 2008-09. -------Hospira gets FDA nod for anti-infective drug.

Scientific Journals------Human-2009.

-Creating a cohort area to limit transmission of pandrug-resistant Acinetobacter baumannii in a Thai tertiary care center.

Indo-Asian Antibiotic Resistance Scenario - 2009 (by A.J. Tamhankar)Media News-------Sanitation vs. vaccination in cholera control.
From the Scientific Journals------Human-2009.
-Clinical significance and outcome of nosocomial acquisition of spontaneous bacterial peritonitis in patients with liver cirrhosis.

Indo-Asian Antibiotic Resistance Scenario - 2009 (by A.J. Tamhankar) Media News-------16 cholera cases confirmed in Hyderabad.------Ranbaxy to recall antibiotic drug from US market
From the Scientific Journals------Human-2009.
-Risk factors for antibiotic-resistant E. coli in children in a rural area.
-Role of embCAB gene mutations in ethambutol resistance in Mycobacterium tuberculosis isolates from India.
-Treatment of bacterial meningitis: An overview of Cochrane systematic reviews.
-Inhibition of peroxidase-catalyzed iodination by cephalosporins: Metallo-beta-lactamase-induced antithyroid activity of antibiotics.
-Outbreak of meningococcal disease in and around New Delhi, India, 2005-2006: a report from a tertiary care hospital.
-Multiple-pulse drug delivery systems: setting a new paradigm for infectious disease therapy.
Non-Human and General-2009.
-Inhibition of Beta-Lactamase by 1,4-Naphthalenedione from the Plant Holoptelea integrifolia.

Indo-Asian Antibiotic Resistance Scenario - 2009 (by A.J. Tamhankar)

Media News------WHO raises swine flu alert to phase 5 - Pandemic imminent --- ALL YOU NEED TO KNOW ABOUT SWINE-FLU -- Universal flu vaccine edging closer to reality.---India reviews preparations to tackle swine flu.---Hospital-acquired infections on the rise. -----Super-Strong Paint Kills Superbugs. -----Ex-USSR nations, China on brink of a TB epidemic.-----New drugs could counter antibiotic-resistant infections. -----Mobile phones carriers of deadly 'superbug'.

From the Scientific Journals------Human-2009.

-Inducible clindamycin resistance among clinical isolates of Staphylococci will help in guiding therapy- ----A simple broth-disk method to determine the MIC of ceftriaxone on Salmonella enterica serovar typhi ----- Application of 16S rDNA based seminested PCR for diagnosis of acute bacterial meningitis.-- -------- mutations and rpsL gene with streptomycin resistance in isolates of M. tuberculosis in India---------

-Minimum inhibitory concentration of carbapenems and tigecycline against Salmonella spp.

-Application of 16S rDNA based seminested PCR for diagnosis of acute bacterial meningitis.

-Association of mutations in rpsL gene with high degree of streptomycin resistance in clinical isolates of Mycobacterium tuberculosis in India.

-Malaria - Change in therapeutic policy.

-Role of acute viral hepatitis as a confounding factor inantituberculosis treatment induced hepatotoxicity.

-Surveillance of invasive pneumococcal disease in Colombo, Sri Lanka.

-Newer strategies for the kala-azar elimination programme in India.

-Antibiotic resistance in acne.

-Structural and functional divergence among seven WhiB proteins of Mycobacterium tuberculosis.

-Antibiotic use, environment and antibiotic resistance: A qualitative study in India.

-A Case of Multidrug-Resistant Salmonella enterica Serovar Typhi Treated with a Bench to Bedside Approach.

-Acquired drug resistance pattern in tuberculosis cases at the State Tuberculosis Centre, Delhi, India.

-Assessing clonality of Vibrio cholerae strains isolated during four consecutive years (2004 - 2007) in Iran.

-Increasing incidence of fluoroquinolone-resistant Mycobacterium tuberculosis in Mumbai, India.

-Re-emerging chloramphenicol sensitivity and emerging low level ciprofloxacin resistance among Salmonella enterica serotype typhi isolates in North India.

-Antibiotic resistance in Escherichia coli (EPEC) clinical isolates.

-Antimycobacterial activity of novel N-(substituted)-2-isonicotinoylhydrazinocarbothioamide endowed with high activity towards isoniazid resistant tuberculosis.

-Antimycobacterial activities of novel fluoroquinolones.

-Comparison of cefoxitin disc diffusion test, oxacillin screen agar, and PCR for mecA gene for detection of MRSA.

-Rapid speciation of 15 clinically relevant mycobacteria with simultaneous detection of resistance to rifampin, isoniazid, and streptomycin in Mycobacterium tuberculosis complex.

-A prospective, descriptive study to identify the microbiological profile of chronic wounds in outpatients.

-Role of embCAB gene mutations in ethambutol resistance in Mycobacterium tuberculosis isolates from India.
-Increasing isolations of Neisseria meningitides serogroup A from blood and cerebrospinal fluid in Dhaka, Bangladesh, 1999-2006.
-Drug resistance and genotypic analysis of Mycobacterium tuberculosis strains from Thai tuberculosis patients.
-Clostridium difficile infections in a Shanghai hospital: antimicrobial resistance, toxin profiles and ribotypes.
-Decreasing prevalence of levofloxacin-resistant Streptococcus pneumoniae in Hong Kong, 2001 to 2007.
-TR-700 in vitro activity against and resistance mutation frequencies among Gram-positive pathogens.
-In Vitro Susceptibilities of Aerobic and Facultatively Anaerobic Gram-Negative Bacilli Isolated from Patients with Intra-Abdominal Infections Worldwide: 2005 Results from Study for Monitoring Antimicrobial Resistance Trends (SMART).
-Causative agent distribution and antibiotic therapy assessment among adult patients with community acquired pneumonia in Chinese urban population.
-Neonatal infections in Asia.
-Surveillance for invasive Streptococcus pneumoniae disease among hospitalized children in Bangladesh: antimicrobial susceptibility and serotype distribution.
-Invasive pneumococcal disease in Kanti Children's Hospital, Nepal, as observed by the South Asian Pneumococcal Alliance network.
-The expanding spectrum of disease due to salmonella: an international perspective.
-Antibacterial activity of telithromycin and comparators against pathogens isolated from patients with community-acquired respiratory tract infections: the Prospective Resistant Organism Tracking and Epidemiology for the Ketolide Telithromycin study year 5 (2003-2004). -Attributable mortality of imipenem-resistant nosocomial Acinetobacter baumannii bloodstream infection.
-Variation in Salmonella enterica serovar typhi IncHI1 plasmids during the global spread of resistant typhoid fever.
-Surveillance of antimicrobial resistance of Salmonella enterica serotype Typhi in seven Asian countries.
-Comparative in vitro activity of tigecycline and other antimicrobials against Gram-negative and Gram-positive organisms collected from the Asia-Pacific Rim as part of the Tigecycline Evaluation and Surveillance Trial (TEST).
-Detection and genetic characterisation of qnrB in hospital isolates of Klebsiella pneumoniae in Singapore.
-Constitutive and inducible clindamycin resistance in Staphylococcus aureus and their association with meticillin-resistant S. aureus (MRSA): experience from a tertiary care hospital in Nepal.
-Application of denaturing HPLC to rapidly identify rifampicin-resistant Mycobacterium tuberculosis in low- and high-prevalence areas.
-Molecular characterization and antimicrobial susceptibility of Salmonella isolates from infections in humans in Henan Province, China.
-Antibiotic use in pulmonology wards of Chinese children's hospitals: 2002-2006.
-Staphylococcus aureus disease and drug resistance in resource-limited countries in south and east Asia.
-Genetics and function of the capsules of Burkholderia pseudomallei and their potential as therapeutic targets.
-Resistance of nasopharyngeal pathogens and antimicrobial prescription rates for children in an area under controlled antimicrobial use.
-Minor contribution of mutations at iniA codon 501 and embC-embA intergenic region in ethambutol-resistant clinical Mycobacterium tuberculosis isolates in Kuwait.
-Antibiotic resistance in China--a major future challenge.
-Plasmid-mediated 16S rRNA methylases in aminoglycoside-resistant Enterobacteriaceae isolates in Shanghai, China.
-Impact of enhanced infection control at 2 neonatal intensive care units in the Philippines.
-Campylobacter jejuni peritonitis and bacteremia in a patient undergoing continuous ambulatory peritoneal dialysis.
-Community-acquired urinary tract infections in Southern Turkey: etiology and antimicrobial resistance.
-How to handle a CA-MRSA outbreak.
-Nasopharyngeal carriage and antibiotic resistance of Haemophilus influenzae, Streptococcus pneumoniae and Moraxella catarrhalis in healthy school children in Turkey.
-Trends in antimicrobial resistance of fecal Shigella and Salmonella isolates in Tehran, Iran.
-Nosocomial outbreak of infection with multidrug-resistant Acinetobacter baumannii in a medical center in Taiwan.
-Daily half-dose linezolid for the treatment of intractable multidrug-resistant tuberculosis.
-Characterization of Salmonella enterica isolates from infants and toddlers in Wuhan, China.
-Emergence and widespread dissemination of OXA-23, -24/40 and -58 carbapenemases among Acinetobacter spp. in Asia-Pacific nations: report from the SENTRY Surveillance Program.
-Results of use of WHO Global Salm-Surv external quality assurance system for antimicrobial susceptibility testing of Salmonella isolates from 2000 to 2007.
-Results from the ARTEMIS DISK Global Antifungal Surveillance Study, 1997 to 2007: 10.5-year analysis of susceptibilities of noncandidal yeast species to fluconazole and voriconazole determined by CLSI standardized disk diffusion testing.
-Ciprofloxacin-resistant Salmonella enterica serovar typhi from Kuwait with novel mutations in gyrA and parC genes.
-Increasing drug resistance of Mycobacterium tuberculosis in a medical center---what about in Taiwan overall?
-Comparison of three different PCR-based methods to predict the penicillin nonsusceptible Streptococcus pneumoniae isolates from China.
-The therapeutic efficacy of sulfadoxine/pyrimethamine against Plasmodium falciparum in Yemen.
-Neisseria gonorrhoeae infections.
-Multidrug resistant gram-negative bacteria in clinical isolates from Karachi.
-In-depth molecular characterization of Mycobacterium tuberculosis from New Delhi--predominance of drug resistant isolates of the 'modern' (TbD1) type.
-Staphylococcus aureus bacteraemia in a tropical setting: patient outcome and impact of antibiotic resistance.
-Empirical treatment for pediatric urinary tract infection and resistance patterns of uropathogens, in Queen Alia hospital and prince A'Isha military center--Jordan.
-Is standardized treatment appropriate for non-XDR multiple drug resistant tuberculosis cases? A clinical descriptive study.
-Multidrug resistant enteroaggregative Escherichia coli diarrhoea in rural southern Indian population.
-M. tuberculosis Central Asian Strain 1 MDR isolates have more mutations in rpoB and katG genes compared with other genotypes.
-Predominance of CTX-M-15 extended spectrum beta-lactamases in diverse Escherichia coli and Klebsiella pneumoniae from hospital and community patients in Kuwait.
-Epidemiology of invasive pneumococcal disease in the Arabian Peninsula and Egypt.
-Diversity of carbapenem resistance mechanisms in Acinetobacter baumannii from a Taiwan hospital: spread of plasmid-borne OXA-72 carbapenemase.
-Ertapenem resistance among extended-spectrum-beta-lactamase-producing Klebsiella pneumoniae isolates.
-The epidemiology of gonorrhoea in Norway, 1993-2007: past victories, future challenges.
-Surveillance of invasive pneumococcal disease in Colombo, Sri Lanka.
-Prevalence and characteristics of aac(6')-Ib-cr in AmpC-producing Enterobacter cloacae, Citrobacter freundii, and Serratia marcescens: a multicenter study from Korea.
-Epidemiology and susceptibilities of methicillin-resistant Staphylococcus aureus in Taiwan: emphasis on chlorhexidine susceptibility.
-Nationwide surveillance of antimicrobial resistance among non-fermentative Gram-negative bacteria in Intensive Care Units in Taiwan: SMART programme data 2005.
-In vitro activity of tigecycline against colistin-resistant Acinetobacter spp. isolates from Korea.
-Characterisation of genes encoding aminoglycoside-modifying enzymes among meticillin-resistant Staphylococcus aureus isolated from two hospitals in Tehran, Iran.
-Susceptibility of Candida albicans to common and novel antifungal drugs, and relationship between the mating type locus and resistance, in Lebanese hospital isolates.
-Epidemiologic characterization of nosocomial Acinetobacter baumannii infections in a Turkish university hospital by pulsed-field gel electrophoresis.
-Prevalence of plasmid-mediated quinolone resistance determinants over a 9-year period.
-First report on a hyperepidemic clone of KPC-3-producing Klebsiella pneumoniae in Israel genetically related to a strain causing outbreaks in the United States.
-Prevalence of primary fluoroquinolone resistance among clinical isolates of Helicobacter pylori at a University Hospital in Southern Taiwan.
-Dual-priming oligonucleotide-based multiplex PCR for the detection of Helicobacter pylori and determination of clarithromycin resistance with gastric biopsy specimens.
-Emergence of community-associated methicillin-resistant Staphylococcus aureus strains as a cause of healthcare-associated bloodstream infections in Korea.
-Recovery of both vancomycin-resistant enterococci and methicillin-resistant Staphylococcus aureus from culture of a single clinical specimen from colonized or infected patients.
-Validation of the line-probe assay for rapid detection of rifampicin-resistant Mycobacterium tuberculosis in Vietnam.
-Rapid emergence of third generation cephalosporin resistant Shigella spp. in Southern Vietnam.

Non-Human and General-2009.

-Surface water of a perennial river exhibits multi-antimicrobial resistant shiga toxin and enterotoxin producing Escherichia coli.

-Antimicrobial activity of five herbal extracts against multi drug resistant (MDR) strains of bacteria and fungus of clinical origin.

-Evaluation of the activity of 16 medicinal plants against Neisseria gonorrhoeae.

-Self-purificatory Ganga water facilitates death of pathogenic Escherichia coli O157:H7.

-Activity of antibiotics against Fusarium and Aspergillus.

-Animal models of tuberculosis for vaccine development.

-Molecular epidemiological characteristics of Shigella spp. isolated from river Narmada during 2005-2006.

-Identification of Pasteurella multocida isolates of ruminant origin using polymerase chain reaction and their antibiogram study.

-Phenotypic and genotypic characterisation of antimicrobial resistance in faecal bacteria from 30 Giant pandas.
-Isolation, antimicrobial resistance, and virulence genes of Pasteurella multocida strains from swine in China.
-High prevalence of plasmid-mediated quinolone resistance determinants qnr, aac(6')-Ib-cr, and qepA among ceftiofur-resistant Enterobacteriaceae isolates from companion and food-producing animals.
-Identification and characterization of Class 1 integron resistance gene cassettes among Salmonella strains isolated from imported seafood.
-Emergence of plasmid-mediated quinolone resistance genes in Enterobacteriaceae isolated from chickens in China.
-Prevalence of antimicrobial resistance among serotypes of Campylobacter jejuni isolates from cattle and poultry in Japan.
-Bactericidal activity of medicinal plants, employed for the treatment of gastrointestinal ailments, against Helicobacter pylori.
-Analysis of ciprofloxacin-resistant Salmonella strains from swine, chicken, and their carcasses in Taiwan and detection of parC resistance mutations by a mismatch amplification mutation assay PCR.
-Outbreaks of Shigella sonnei infections in Denmark and Australia linked to consumption of imported raw baby corn.

GLOBAL ANTIBIOTIC RESISTANCE INITIATIVE

Resources for the Future, USA, has launched GLOBAL ANTIBIOTIC RESISTANCE INITIATIVE with focus on five emerging economies – India, China, South Africa, Kenya, and Vietnam http://www.rff.org/News/Press_Releases/Pages/Global_Antibiotic.aspx

Wake up India
MRSA found in poultry in a study in Belgium /EID/
“US running out of drugs to treat deadly bug”; ChinaView presents an article from L. A. about gram-negative MDR, focusing mostly on Acinetobacter baumannii .. and CNN warning for more resistance among gram-negatives.
CVMP (COMMITTEE FOR MEDICINAL PRODUCTS FOR VETERINARY USE) of EMEA, has produced http://www.emea.europa.eu/pdfs/vet/sagam/8173006enfin.pdf
read the summary on page 23-24
CLSI Publishes Guideline For Analysis And Presentation Of Cumulative Antimicrobial Susceptibility Test Data Analysis and Presentation of Cumulative Antimicrobial Susceptibility Test Data; Approved Guideline-Third Edition (M39-A3).
Published online 19 February 2009 Nature doi:10.1038/news.2009.110
Wheat genes could help fight fungal epidemics. As farmers around the world anxiously monitor the march of a deadly orange fungus across their wheat fields, two research groups have reported progress in the battle against the lethal scourge: the cloning of two fungus-fighting genes. This idea could be borrowed for humans- A.J. Tamhankar
Published online 22 February 2009 Nature doi:10.1038/news.2009.116
New antibodies block a range of influenzas. Discovery hints at the possibility of broad-spectrum vaccines. Researchers have identified a group of antibodies that neutralize a wide range of influenza viruses, including the H5N1 avian influenza, the 1918 Spanish flu and some seasonal strains. These molecules may one day be used therapeutically to protect patients against a broad array of strains.

Occurrence of antibiotics and antibiotic resistant bacteria in hospital associated waters in India

A team of Indian scientists from R.D.Gardi Medical College, Ujjain and a Swedish scientist from Karolinska Institute recently presented preliminary findings of their collaborative study at the National Conference of IPHA, (Bangalore, 9-11 January 2009) and at the IAPSM Conference, (Aurangabad, 21-23 January 2009), in which they reported occurrence of Metronidazole, sulfamethoxazole, ofloxacin, norfloxacin, levofloxacin, tinidazole and ciprofloxacin in the range of 1.4 to 236.00 µg/L in the waste water of two Indian hospitals. E. coli isolates from the hospital waste water samples showed resistance to third generation cephalosporins and fluoroquinolones. The impact of such an occurrence on public health and environment of India needs to be evaluated.
The scientists will soon start communicating their results to Research Journals.

Antibiotics in Pharma waste water

World's highest drug levels entering India stream - Yahoo! News
Enough of a single, powerful antibiotic was being spewed into one stream ... The water in a river in India could be the rain coming down in your town in a news. yahoo.com/s/ap/20090125/ap_on_re_as/pharmawater_india - 107k
PMO orders testing of Patancheru water
28 Jan 2009, TNN
NEW DELHI: Concerned over reports of water at Patancheru in Medak near Hyderabad containing drug residues that are as high as 150 times the levels
detected in US, PMO has asked for testing of samples and a report on the composition of the pharmaceutical cocktail within a week.

National conference On Antimicrobial Resistance

Announcement
National conference On Antimicrobial Resiatance: from emerging Threat to Reality.
Dates: 23-25 March 2009.
Venue: Allahabad Agricultural Institute.
website- http://www.aaidu.org/
email: antimicro09@gmail com

Last Date for sending Abstracts: 10th February 2009

ABR gene in genetically engineered Brinjal

Dear friends
Dr. Mira Shiva informs that
A company in India is developing genetically engineered Brinjal incorporating the Bacillus thuringiesis gene.
The Antibiotic Resistant Marker being used for Bt Brinjal is NEOMYCIN . Horizontal transfer of genes & Genetic pollution & other Public Health Concerns need to be addressed as Biosafety studies done by the Company are inadequate. The GEAC Meets on 14th Jan 09.
All of you need to comment on this proposal in this space so that Dr. Mira Shiva takes it up at the appropriate forum.